INTERVENTIONELLE, MEDIKAMENTÖSE STUDIEN
Titel
A Prospective, Open-label, Multicentre, Randomized, Phase-3-trial of Acalabrutinib, Obinutuzumab and Venetoclax (GAVE) Compared to Obinutuzumab and Venetoclax (GVE) in Previously Untreated Patients With High Risk (17P-deletion, TP53-mutation or Complex Karyotype) Chronic Lymphatic Leukemia (CLL)
Indikation
Chronic Lymphatic Leukemia (CLL)
Art der Studie
Therapiestudie, Interventionell, Phase 3
Therapielinie
Erstlinientherapie
Hauptprüfer am Zentrum (PI)
Prof. Dr. med. C. Dierks
Ansprechpartner
J. Sen
Telefon: 0345/ 557 4853
Mail: ectu@uk-halle.de
Titel
A prospective randomized phase I/II trial of venetoclax treatment (26 cycles) with 6 cycles or 12 cycles of epcoritamab in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma
Indikation
Chronic Lymphatic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Art der Studie
Therapiestudie, Interventionell, Phase 2
Therapielinie
ab Zweitlinientherapie
Hauptprüfer am Zentrum (PI)
Prof. Dr. med. C. Dierks
Ansprechpartner
J. Sen
Telefon: 0345/ 557 4853
Mail: juliane.sen@uk-halle.de
Titel
A Multicenter, Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of Venetoclax-Obinutuzumab Retreatment in Patients With Recurring Chronic Lymphocytic Leukemia
Indikation
Chronic Lymphatic Leukemia (CLL)
Art der Studie
Therapiestudie, Interventionell, Phase 2
Therapielinie
Zweitlinientherapie
Hauptprüfer am Zentrum (PI)
Prof. Dr. med. C. Dierks
Ansprechpartner
A. Kleinbauer
Telefon: 0345/ 557 1386
Mail: antje.kleinbauer@uk-halle.de
Titel
A Phase 3, Randomized Study to Compare Nemtabrutinib Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in Participants With Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Indikation
Chronic Lymphatic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Art der Studie
Therapiestudie, Interventionell, Phase 3
Therapielinie
Erstlinientherapie
Hauptprüfer am Zentrum (PI)
Prof. Dr. med. C. Dierks
Ansprechpartner
J. Sen
Telefon: 0345/ 557 4853
Mail: juliane.sen@uk-halle.de