Programm

Treffen für Nachwuchswissenschaftler

08:30 - 09:00
Frühaufsteher-Snack (nur für Studenten, Doktoranden und Post-Docs)

09:00 - 09:10
Willkommensgruß 
Ivonne Regel, Tony Gutschner, Jonas Rosendahl

09:10 - 11:15    
Befähigung der nächsten Forschergeneration:
Programm gestaltet von Doktoranden des RTG2751 in Zusammenarbeit mit dem Deutschen Pankreaskrebsforschungsnetz
Sitzungsleiter: RTG2751/CRU325/CRU5002/CRC1321

09:10 - 09:30
Interaktiver Start - Icebreaker

09:30 – 10:20
Offene Podiumsdiskussion
Albrecht Neeße, Göttingen; Francisco X. Real, Madrid; Arina Wasner

10:20 - 10:35
Kaffeepause

10:35 - 11:15 
From despair to delight – publishing from the authors and editors’ perspective
Albrecht Neeße, Göttingen

11:15 - 12:00 
Mittagsimbiss

12:00
Willkommensgruß Hauptkonferenz
Jonas Rosendahl, Ivonne Regel, Tony Gutschner

Session 1: Früh ist der Schlüssel - Biomarker und Ansätze zur Früherkennung von Pankreaskarzinomen 
Chair Session 1: Patrick Michl, Heidelberg / Atul Verma, Halle (Saale)

12:10 - 12:35
Understanding the early events in PDAC development are key for a better treatment
Francisco X. Real, Madrid

12:35 - 12:50
Coxsackievirus B Infections as Drivers of Pancreatic Cancer Development
Peter Storz, Jacksonville

12:50 - 13:05
Obesity is shaping an immunosuppressive pancreatic microenvironment promoting PDAC in mice
Anne-Kristin Fritsche, Halle (Saale)

13:05 - 13:30
PDAC Precursor lesion – How to stratify the cancer risk
Irene Esposito, Düsseldorf

13:30 - 14:00 
Kaffee und Kuchen

Session 2: Aktuelle Standards und neue Behandlungsmöglichkeiten bei PDAC
Chair Session 2: Dieter Saur, München / Volker Ellenrieder, Göttingen

14:00 - 14:25
Current options for early pancreatic cancer detection in the clinic and beyond
Julia Mayerle, München

14:25 - 14:50
Surgery in PDAC – Still the most promising approach?
Michael Ghadimi, Göttingen

14:50 - 15:05
Vascular resections for PDAC: Pushing the boundaries
Ulrich Ronellenfitsch, Halle (Saale)

15:05 - 15:20
Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells
Maj-Britt Paulsohn, Göttingen

15:20 - 15:45
How will we treat PDAC patients in 10 years?
Hana Algül, München

15:45 - 17:00 
Poster-Session A (mit Kaffee und Kuchen)

17:15 - 18:00 
Chair Keynote Lecture 1:
Thomas Gress, Marburg / Nehir Sahin, Göttingen

New biomarkers on the horizon (or why not)?
Nuria Malats, Madrid

18:30 Get-together (Leopoldina)

Session 3: Zelluläre Heterogenität des Pankreaskarzinoms
Chair Session 3: Jörg Kleeff, Halle (Saale) / Joana Oschwald, Göttingen

08:00 - 08:25
Neutrophil-driven inflammation in PDAC progression
Dieter Saur, München

08:25 - 08:40
Context-specific role of SNAI2 in modulating lineage-specific 
transcription factor networks in PDAC
Akshay Kanakan, Stuttgart 

08:40 - 08:55
Exploring lineage plasticity in patient-derived in vitro and in vivo models of PDAC
Joana Oschwald, Göttingen 

08:55 - 09:20
Models to understand cell plasticity in PDAC development
Alexander Kleger, Ulm

09:20 - 09:45 
Novel insights into cancer-associated fibroblast heterogeneity 
Daniel Öhlund, Umea

09:45 - 10:50 Kaffeepause

Session 4: Neue Modelle und Ansätze zur Untersuchung von Pankreaskarzinom
Chair Session 4: Günter Schneider, Göttingen / Ilse Rooman, Brüssel

10:50 - 11:15 
Modelling Tumor Cell States and Ecosystem Interactions in Pancreatic Cancer
Maximilian Reichert, München

11:15 - 11:30 
Mitogen-Induced Acinar Proliferation: Functional Equipotency and Oncogenic Selection
Jonathan Baldan, Brüssel

11:30 - 11:45 
Precision-cut tissue slices of human pancreatic ductal adenocarcinoma (PDAC): morphological and immunohistochemical analysis with comparison to resected specimen and organoids
Jovan Todorovic, Göttingen

11:45 - 12:10 
T-cell responses in pancreatic cancer 
Magdalena Huber, Marburg

12:10 - 13:15 Mittagessen

13:15 - 14:30 
Poster-Session B 

14:30 - 15:15 
Chair Key Note Lecture 2: 
Tony Gutschner, Halle (Saale) / Laura Roth, Heidelberg 

Insights into Early and Advanced Pancreatic Cancer from Spatial Profiling (virtueller Vortrag)
Anirban Maitra, New York

15:15 - 15:45 Kaffee und Kuchen

Session 5: RNA-Biologie trifft PDAC
Chair Session 5: Stefan Hüttelmaier, Halle (Saale) / Mobina Kiani, Halle (Saale)

15:45 - 16:10 
Targeting the Integrators: IGF2BPs at the Crossroads of PDAC Progression and Immune Evasion
Nadine Bley, Halle (Saale)

16:10 - 16:25 
An alternative translation program underlies tumor-suppressive effects of TGF-β in early pancreatic carcinogenesis
Pit Preckwinkel, Halle (Saale)

16:25 - 16:40 
KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival
Thomas Ekstrom, Stuttgart

16:40 - 17:05 
LncRNAs – Promising targets in PDAC?
Roland Rad, München

17:30  Führungen durch die Leopoldina oder die Meckelschen Sammlungen (optional)   

19:30  Kongress-Dinner (Bergschenke)

07:30 - 08:15 Pancreatic Cancer Run 
Lauf-Guides: Jörg Kleeff und Tony Gutschner
Treffpunkt: Marktplatz/Händel-Denkmal; Distanz: 5 km

Session 6: Neue Themen bei PDAC - Teil 1
Chair Session 6 - Teil 1: Monika Hämmerle, Halle (Saale) / Uddipta Biswas, Heidelberg

09:00 - 09:25
Understanding and exploiting ARDI1A-deficiency in pancreatic cancer
Elisabeth Heßmann, Göttingen

09:25 - 09:50
Stroma is key in PDAC treatment
Corinne Bousquet, Toulouse

09:50 - 10:05
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer
Anna Brichkina, Marburg

10:05 - 10:20
Targeting transcriptional addiction to anti-senescence programs in pancreatic cancer
Adi Mackay, Göttingen

10:20 - 10:45 Kaffeepause

Session 6: Neue Themen bei PDAC - Teil 2
Chair Session 6 - Teil 2: Malte Buchholz, Marburg / Florian Döbbe, Göttingen

10:45 - 11:10
Spatial mapping of the human pancreatic duct unveils a basal and luminal cell types with distinct representation in cancer subtypes
Ilse Rooman, Brüssel

11:10 - 11:35 
New insights into ADM development   
Roland Schmid, München

11:35 - 12:00 
Genomic instability and cellular plasticity in pancreatic cancer progression
Barbara Grüner, Essen

12:00 - 12:30
Preisverleihung & Verabschiedung inkl. Snacks vor der Abreise
Jonas Rosendahl, Ivonne Regel, Tony Gutschner