Completed Projects

Contact:                Prof. Dr. Rafael Mikolajczyk, Johannes Horn, PhD

Duration:                June 2017 – May 2020

Funding:                 BMBF (Federal Ministry of Education and Research) 

More information can be found here



Multi resistant Enterobacteriaceae (MDR-E) are a significant threat to public health in many European countries. While traditional Infection Control strategies are primarily aimed at curbing the transfer within a hospital, a growing number of findings underline the importance of patient traffic between hospitals to disseminate MDR-E within health systems. The EMerGE-NeT-consortium goes beyond the previous research results and combines expertise in theoretical modeling, numerical simulation studies, epidemiology, clinical medicine, and microbiology to develop a generic network modeling platform that combines the transfer of MDR-E between and within hospitals.



  • Institute of Hygiene and Environmental Medicine, Charité- University Medicine, Germany
  • Department of Microbiology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Poland
  • UMC Utrecht, Julius Centre for Health Sciences & Primary Care, Netherlands
  • Department of Medicine E; Rabin Medical Center, Beilinson Hospital, Israel
  • Clinic of infectious diseases, microbiology and preventive medicine, University hospital Virgen Macarena, Spain
  • University of Warsaw, Faculty of Mathematics, Informatics and Mechanics, Institute of Applied Mathematics and Mechanics, Poland
  • AOK Bayern
  • AOK Niedersachsen
  • AOK Plus
  • Universitätsklinikum Halle (Saale)
  • Klinikum Braunschweig



Belik V, Karch A, Hövel P, Mikolajczyk R (2017) Leveraging topological and temporal structure of hospital referral networks for epidemic control. Edited by N. Masuda, Petter Holme (Springer, Berlin, Heidelberg) 

Belik V, Mikolajczyk R, Hövel P (2016) Control of epidemics on hospital networks. Edited by E. Schöll, S. H. L. Klapp, P. Hövel (Springer, Berlin, Heidelberg) 

The RESCEU project aims to develop robust evidence on RSV disease burden and economic impact; create a sustainable Europe-wide multidisciplinary, multi-stakeholder community from academia, public health, scientific societies, patient organizations, regulatory agencies, and industry; and provide infrastructure to perform future pivotal trials for RSV vaccines and therapeutics.


  • Respiratory syncytial seasonality and prevention strategy planning for passive immunization of infants in low-income and middle-income countries: a modeling study (May 2021)
  • The burden of respiratory syncytial virus infection during the first year of life (March 2021).

Contact:                   Dr. med. Stefan Moritz, Prof. Dr. med. Rafael Mikolajczyk

Duration:                   since June 2020

More information:



Simulation of the transmission risk of COVID-19 in the context of large indoor sports and cultural events.

The research project RESTART-19 aims to simulate the risk of an outbreak of COVID-19 due to a major event in a closed hall and to investigate the conditions under which such events can be carried out despite the pandemic without risking the health of the general population.

During the experiment in the quarterback real estate Arena in Leipzig, vast amounts of data were created in August 2020. "Thanks to the active participation and enormous support of the participants, we were now able to develop a mathematical model, that shows which concepts should be implemented in mass gathering events in order to minimize the risk of SARS-CoV-2 transmission," explains Dr. med. Stefan Moritz, Study Guide of the Restart-19 project at the University Medicine Halle (Saale).

The trans-national project "Restart-19" of the University Medicine Halle (Saale) is supported by the Ministry of Economics, Science and Digitization of the Land of Saxony - Anhalt and the Ministries for Science, Culture and Tourism or Social Affairs and Social Cohesion of the Free State of Saxony. Partner of the project are the SC DHFK Leipzig, Handball, and the ZSL operator company mbH.

Important publications:

Moritz S*, Gottschick C*, Horn J, Popp M, Langer S, Klee B, Purschke O, Gekle M, Ihling A, Mikolajczyk R. The Risk of Indoor Sports and Culture Events for the Transmission of COVID-19 (RESTART-19). medRxiv preprint doi: *shared first authorship